How do we infer which genes orchestrate various processes in the cell? How did humans migrate out of Africa and spread around the world? In this class, we will see that these two seemingly different questions can be addressed using similar algorithmic and machine learning techniques arising from the general problem of dividing data points into distinct clusters.
Genomic Data Science and Clustering (Bioinformatics V)
Genomic Data Science and Clustering (Bioinformatics V)
This course is part of Bioinformatics Specialization
Instructors: Pavel Pevzner
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4.1
(93 reviews)
Intermediate level
Some related experience required
9 hours to complete
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Learn at your own pace
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3 assignments
Taught in English
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This course is part of the Bioinformatics Specialization
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There are 3 modules in this course
<p>Welcome to class!</p><p>At the beginning of the class, we will see how algorithms for <strong>clustering </strong>a set of data points will help us determine how yeast became such good wine-makers. At the bottom of this email is the Bioinformatics Cartoon for this chapter, courtesy of <a href="http://bearandfox.com" target="_blank" title="Link: http://bearandfox.com">Randall Christopher</a> and serving as a chapter header in the Specialization's bestselling <a href="http://bioinformaticsalgorithms.com" target="_blank">print companion</a>. How did the monkey lose a wine-drinking contest to a tiny mammal? Why have Pavel and Phillip become cavemen? And will flipping a coin help them escape their eternal boredom until they can return to the present? Start learning to find out!</p><p><img width="550" alt="" src="http://bioinformaticsalgorithms.com/images/cover/clustering_cropped.jpg" title="Image: http://bioinformaticsalgorithms.com/images/cover/clustering_cropped.jpg"></p>
What's included
5 videos2 readings1 assignment2 app items
<p>Welcome to week 2 of class!</p> <p>This week, we will see how we can move from a "hard" assignment of points to clusters toward a "soft" assignment that allows the boundaries of the clusters to blend. We will also see how to adapt the Lloyd algorithm that we encountered in the first week in order to produce an algorithm for soft clustering. We will also see another clustering algorithm called "hierarchical clustering" that groups objects into larger and larger clusters.</p>
What's included
5 videos1 reading1 assignment2 app items
What's included
2 readings1 assignment
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4.0 (7 ratings)Offered by
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Reviewed on Jun 9, 2017
the part about EM is the best I know, and first time I understand the EM algorithm.
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In depth and comprehensive coverage of the topics in genetic data analysis.
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Reviewed on Mar 21, 2020
Really enjoyed the clustering chapters and the practical exercises with the yeast dataset
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